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These nonseroconverters include people on B-cell-depleting therapy or people with inborn errors of immunity, as these individuals are typically more susceptible to prolonged infection and higher rates of progression to severe disease [36, 37]

This approach may be particularly valuable in studies examining how different signaling systems overlap during regeneration and structural remodeling

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If the vitamin is administered by injection in response to a deficiency and enters the bloodstream directly in high concentrations, an immunologic reaction with skin reactions is possible