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It is believed that GLP-1RAs induce vasodilation through action of the proximal tubular cells and stimulating urinary sodium excretion [68, 72]

Patients should also be informed that early plateaus are common and do not indicate treatment failure

Blood pressure, C-reactive protein, and risk of future cardiovascular events

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Osmotic diuresis by SGLT2 inhibition stimulates vasopressin-induced water reabsorption to maintain body fluid volume

Carnitine deficiency: a possible cause of gastrointestinal dysmotility