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2008;47 Suppl 3:4-24

Consult a healthcare professional before administering this injection

In vitro , butyrate increased the expression of mitogen-activated protein kinase phosphatase-1 (MKP-1), which dephosphorylates activated c-Jun N-terminal kinase (JNK), ERK1/2, and p38 Mitogen-activated protein kinase (MAPK) to counteract excessive inflammation in RAW264.7 macrophages (214)

As CYP8B1 acts to catalyze 12-hydroxylation and is required for CA synthesis, it serves as a master regulator for the BA composition