When AT-II production increases above normal levels, it induces vascular remodeling and endothelial dysfunction in association with increases in the levels of blood pressure
Stres oksidatif terjadi ketika ada ketidakseimbangan antara produksi radikal bebas dan kemampuan tubuh untuk melawannya
Similarly, animals with deficiencies in indirect scavengers of ROS, such as sulfiredoxin and metallothionein, are highly susceptible to alcohol-induced hepatic injury 27,31
S-glutathionylation in protein redox regulation
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S5A, B) and ferroptosis inhibitor Fer-1 effectively reduces inflammation, evidenced by decreased F4/80 and Ly6G immune cell infiltration (Fig