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First, rapid dose escalation increases the likelihood and severity of GI side effects, which are particularly problematic for patients with IBD, celiac disease, or other GI-affecting autoimmune conditions

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GLP-1 agonists work primarily in the gastrointestinal tract and specific brain regions involved in appetite regulation, while stimulants act broadly on dopamine and norepinephrine pathways throughout the nervous system

It can increase stamina, as it increases blood flow and nitric oxide

Injecting Ozempic into a different spot each week minimizes your chances of developing scar tissue

For a full list of potential warning signs for these conditions, please see the Mayo Clinics Semaglutide resources