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Angiogenesis and cellular migration model studies

Its main mechanism of action is based on increasing the expression of BDNF (Brain-Derived Neurotrophic Factor) and its TrkB receptors in the hippocampus and prefrontal cortex, promoting synaptic plasticity, long-term potentiation (LTP), and memory consolidation (Dolotov et al., Neuroscience 2006)

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Robertson et al., 2016), left lenticular nucleus(Harada et al., 2011), occipital cortex(Drenthen et al., 2016

Nature Microbiology , 9 (7), 18561872

Although originally intended for individuals with type 2 diabetes, metformin has proven effective in pregnancy programsespecially for women with PCOS or obesity