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first reported that the administration of CBM588 improved the ecosystem of the gastrointestinal tract in mice significantly, modulating the gut microbiota composition, increasing the numbers of Bifidobacterium , Coprococcus , and Bacteroides , enhancing butyrate production, and reducing epithelial damage (Hagihara et al., 2018)

From there, vitamin B12 combines with a protein called intrinsic factor so that it can be absorbed further down in the small intestine