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Most patients lose 15 pounds in 8 to 16 weeks on GLP-1 medications Tirzepatide may produce slightly faster results than Semaglutide Appetite suppression often begins within the first 12 weeks Healthy weight loss averages 1 to 2.5 pounds per week Results depend on dosing, nutrition, activity, and consistency GLP-1 medications such as Semaglutide (Wegovy, Ozempic) and Tirzepatide (Zepbound, Mounjaro) are widely used in medical weight loss programs to help reduce appetite and support gradual fat loss

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Ozempic (semaglutide) targets one hormonal pathway involved in appetite control, while Zepbound (tirzepatide) targets two