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Addressing obesity through weight management strategies, including pharmacologic ones like GLP-1 receptor agonists, is a key component of reducing all operative risks, improving surgical outcomes, and enhancing the long-term success of orthopedic interventions

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These systems retain Eugenols functionality while achieving slow, sustained drug release, and can be triggered to release in response to specific environmental stimuli, thereby avoiding the cytotoxicity associated with long-term high-concentration release, improving biosafety (Khan et al., 2019