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Mast cell activation may facilitate the entry of pathogenic antibodies into the CNS by disrupting the blood-brain barrier and attracting additional immune cells into neural tissue

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5-Amino-1MQ: cellular methylation, SAM levels, adipose energy expenditure

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Different insults induce brain tissue damage and lead to neuronal cell death such as ischemic injury, oxidative stress, and glutamate toxicity (Figure 4)