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If you've been consistent with daily dosing, proper reconstitution, and refrigerated storage, and still see zero change at 16 weeks, the issue is likely absorption or individual receptor sensitivity rather than insufficient dose

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If you notice any one of these symptoms while on this medication, it could be a sign that your body has not adapted to the dosage and that you should switch back to lower doses to avoid getting these side effects

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Eating patterns established

The relationship between blood glucose fluctuations and vision changes is well-established in diabetes care and represents the most likely explanation for blurry vision in patients taking metformin