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The Cas9-sgRNA construct of aptf-2 was obtained using PCR to insert the target sequence: (GCCAACTGAATCAAAGCCAGAGG) into pDD162 (Addgene #47549)

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J Alzheimers Dis 2017;57:353-71

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That puts it in the same broad therapeutic conversation as injectable GLP-1 drugs, but not in the same format

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In this study, a multifunctional dimeric copper peptide incorporated hydrogel, G/D-CuP has been developed as an innovative wound dressing to promote diabetic wound healing

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Studies using GIP-Cre mice have demonstrated that GIP receptors are expressed in key brain regions involved in feeding regulation, including the ARC, paraventricular nucleus (PVN), and DMH of the hypothalamus, as well as the area postrema (AP) of the medulla [31]

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