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Authors' contributions: JS and DF participated in the conception and design of the review, revised the whole manuscript, and read and approved the final manuscript

Another topic often discussed in longevity and cardiovascular research is TMAO (trimethylamine N-oxide)

Typically, patients are started on a low introductory dose that allows their bodies to get used to it

These complementary mechanisms induced potent immunogenic cell death that promotes dendritic cell maturation and activates CD8 + T cell responses

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These are crucial for the enzymes activity and are situated within a specific structural motif known as the a/b-hydrolase loop