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This is where most patients are convinced the protocol is working

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Some oral preparations are now available

(PubMed) Whyte EM, Mulsant BH, Butters MA, et al

Methods ICH was modeled by intrastriatal injection of autologous blood and IF was modeled by every-other-day feeding in male control mice (C57BL/6), mice with and microglia specific knockout Sirt3 f/f ;Cx3cr1-Cre (Sirt3 cKO), and Sirt3 f/f (wild-type) mice

By the time it passes through the stomach and into the small intestine, much of the active compound has been neutralized