plateau glp 1 All About the GLP-1 Breaking Through Weight Loss Plateaus

doi: 10.1016/j.neuroscience.2011.02.023 84 FortinSMChenJCPetticordMCRagozzinoFJPetersJHHayesMR

J Toxicol Environ Health

Neuropsychopharmacology (2014) 39:223343

Increased oxidative stress, inflammation and lipotoxicity associated with hyperglycaemia and insulin resistance potentially impair vascular endothelial function and increase endothelial permeability, leading to the penetration of glycated and oxidized low-density lipoprotein (LDL) cholesterol into the endothelium, i.e., initiation of atherosclerosis

Evidence now shows that consistent weight loss occurs when GLP-1 therapy continues, with weight regain beginning 3 to 6 months after discontinuationunderscoring the importance of ongoing treatment strategies

Diabetes Advocacy in the complete 2021 Standards of Care