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Adult-onset nesidioblastosis causing hypoglycemia: an important clinical entity and continuing treatment dilemma

Extremes of gastroparesis can lead to hospitalization due to malnutrition and dehydration caused by food not being properly digested

Based on this model, CerS1 is transported to the outer mitochondrial membrane by the p17/PERMIT to recognize and induce C18:0 ceramide-mediated mitophagy in brain (Oleinik et al., 2023)

Under high blood sugar conditions, oxidative stress and inflammatory responses are enhanced, leading to damage and functional impairment of bone cells (10)

Glutathione plays several key roles: Detoxification

SHK@HA-MPDA effectively inhibited cytoplasmic PKM2 tetramerization and attenuated its nuclear translocation, significantly reducing lactate and ATP production in CT26 cells