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Research Protocol Summary Study Protocol: 0.25 mg AOD-9604 administered intra-articularly via ultrasound guidance Frequency: Weekly injections Duration: 4-7 weeks in research studies Combination Therapy: 6 mg hyaluronic acid co-administered for enhanced effects Assessment Timeline: Significant improvements observed by 8-9 weeks Note: These protocols are from animal research and have not been validated for human use

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Neuroprotection: Protects against ischemic stroke and CNS damage via the gutbrain axis (PMC8504390)

2017;159(Suppl 5):715