Off-label use, such as splitting the dose or microdosing, should only be done under the guidance of a licensed healthcare professional
However, the limited contact time with low concentrations used therapeutically is unlikely to cause significant enamel erosion
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In: Journal of Clinical Medicine
Heterogeneity is seen both in terms of the number of basepair mismatches within the textbook 2 hexamer-containing ARE sequence, the number of hexamers per ARE, and the make-up of the spacing between the individual hexamers in AREs
Lam CSP, Rodriguez A, Aminian A, Ferrannini E, Heerspink HJL, Jastreboff AM, et al