This gap is critical, as metastatic RCC remains incurable with current therapies, and ferroptosis targeting could offer a new avenue to treat advanced disease
Concomitant identification of biomarkers for ferroptosis is also required for more rigorous inclusion/exclusion into clinical trials and robust evaluation/formal testing of novel therapies targeting the ferroptotic cascade
Phentermine is designed to be temporary
Lys05 exhibits enhanced autophagy inhibition and antitumor activity, while DQ661 targets both autophagy and lysosomal function, offering a dual mechanism of action
Majumdar SR, Josse RG, Lin M, Eurich DT
Once researchers discovered methylene blue could safely act as a therapeutic agent, targeting specific biological processes within the body, the question quickly became: what else could it do