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Pregnant or nursing women, individuals under 18, and those with specific health conditions should avoid it unless otherwise advised by a healthcare provider

This signal, however, was not confirmed in the FIGHT trial which showed nonsignificant increases in death or HF hospitalization with liraglutide compared with placebo for patients with HF with reduced ejection fraction (HR: 1.30

Why Doctors and Patients Are Interested The popularity of GLP-1 receptor agonists has skyrocketed in recent years, particularly as branded medications like Ozempic and Wegovy have become household names

Of these, 90.1% had type 2 diabetes and 77.2% had obesity

This leads to reduced food intake and significant weight loss in clinical trials and real-world use

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