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For healthcare systems and policymakers, the evidence supports cautious optimism tempered by realistic acknowledgment of current limitations and the need for comprehensive approaches that address pharmacological efficacy, access, sustainability, and equity concerns

** RDA is not established

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Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

GLP-1 Agonists Although both Metformin and GLP-1 Agonists are related to addressing the metabolic components, their mechanisms of action are different

Arakawa M, Mita T, Azuma K, Ebato C, Goto H, Nomiyama T, Fujitani Y, Hirose T, Kawamori R, Watada H: Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4