In addition, increasing plasma FFA content leads to fatty acid oxidation overload in hepatocytes, induces mitochondrial damage and generates large amounts of ROS, causing oxidative stress, ER stress and inflammatory response, which advances the process of disease progression
Our previous in vitro study indicated that GSSSG exerted an inhibitory effect on proinflammatory gene expression in retinal pigment epithelial cells stimulated with LPS 33
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Zhou X, Xia X, Li L, Ye YMYZJ, Chen Q, Ke M, Cui Q, He Y, Chen Y-T, Lin S-S, Liu W, Wang J (2025) Evaluation of heavy metals and essential minerals in the hair of children with autism spectrum disorder and their association with symptom severity
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Persistent fatigue that interferes with daily activities, unexplained weight changes beyond those expected from the medication's appetite effects, or new onset of heat or cold intolerance warrant medical review