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NICE obesity guidance (CG189) recommends multicomponent interventions addressing diet, physical activity, and behaviour change as first-line management

Small uncontrolled semaglutide and tirzepatide series suggest that extending the same dose to every other week can hold much of a plateau with less drug and may preserve more muscle than active loss

PMID 37973897

BPC-157 Body Protective Compound-157, a pentadecapeptide derived from human gastric juice proteins

For others, the decision to use BPC-157 should involve careful consideration of the limited evidence base, potential risks from unregulated products, and consultation with knowledgeable healthcare providers.

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