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Their activation leads to inhibition of T cell differentiation, downregulation of neutrophil superoxide production, as well as an inhibition of pro-inflammatory cytokine production [76]

One possibility is receptor-mediated or adsorptive transcytosis across brain endothelial cells, although direct evidence for this process is limited and likely molecule-specific

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Baseline determination, follow-up and primary outcome Baseline was defined as the date of the first recorded clinical encounter for T2D in the EMRs, provided that no prior diagnosis of osteoporosis was present at that time