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Biol Psychiatry 2015

Prescribers who rely exclusively on commercial products are one shortage away from having no options for their patients

Improves metabolism

Subjects were randomly allocated to receive one tablet daily of 500 g cobalamin sublingually or orally, or two tablets daily of a vitamin B complex

The absence of validated efficacy data means youre titrating based on subjective experience and hope, not on a known dose-response curve

Adult male SpragueDawley rats (Harlan, Madison, WI, USA) were implanted with jugular vein catheters under 2% isoflurane anesthesia and some rats received femoral arterial catheters 15,78,79