In addition, PFOS can induce autophagy activation with increased Beclin and LC3BII expression through reactive oxygen species (ROS)-mediated extracellular signalregulated kinase (ERK) activation, which is followed by impeded autophagic flux, increased lysosomal membrane permeability (LMP), and, consequently, RTC apoptosis
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Two-way ANOVA revealed a significant interactive effect of LC and TMX on NF-B ( F = 4.793
The dose-related weight loosing properties of liraglutide were evident in a phase II study with increasing doses [37]
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