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N -Acetylcysteine ethyl ester N -Acetylcysteine ethyl ester ( NACET , NAC-Et ) is an antioxidant which acts as a lipophilic prodrug for N -acetylcysteine and subsequently glutathione, with improved bioavailability over N-acetylcysteine itself, and has been researched in animal studies as a potential treatment for diabetic retinopathy

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doi: 10.1111/pedi.13409 8 DeMarsilisAReddyNBoutariCFilippaiosASternthalEKatsikiNet al

Results: Diabetic GK rats exhibited proteinuria, renal interstitial inflammatory infiltrates and fibrosis, which improved by 20 weeks of sitagliptin treatment