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The relationship between semaglutide and diabetic retinopathy is not fully understood, but some studies suggest that a rapid reduction in blood glucose levels may lead to an increased risk of retinal complications

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[55] It suppresses appetite through a dual mechanism: it directly stimulates anorexigenic (satiety-inducing) neurons that express proopiomelanocortin (POMC) and cocaine-and amphetamine-regulated transcript (CART), while simultaneously inhibiting orexigenic (appetite-inducing) neurons that express AgRP and NPY

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