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Due to its high solubility, amphipathic structure, and low molecular weight, melatonin displays a high intracellular and extracellular diffusion capacity, being able to cross cell membranes and the blood-brain barrier [6,15]
DARU Journal of Pharmaceutical Sciences, 22 (1), 40
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10.1080/09513590.2018.1540567 119 LiX.YeH.SuT.HuC.HuangY.FuX.et al (2023c)
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