Disulfidptosis: dysregulated cystine metabolism and disulfide stress Disulfidptosis is a recently identified form of programmed cell death characterized by abnormal intracellular disulfide accumulation, leading to actin cytoskeleton disorganization and redox imbalance [107] (Fig
Additionally, microglial activation is associated with a morphologic transition from ramified to amoeboid-like, adopting a phagocytic phenotype (Woodburn et al., 2021)
Understanding how these surgical procedures induce sustained weight loss and resolution of T2DM holds the key to development of more directed, less invasive therapies
However, more research is needed to support this
Its presence also supports the function of other antioxidants within the body, enhancing their effectiveness
Gene panels, which enable simultaneous analysis of multiple genes associated with specific diseases, are increasingly being adopted in oncology, rare disease diagnostics, and pharmacogenomics