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Finally, participants were filtered on relatedness such that no two people shared more than 700 cM identity by descent 37 , which corresponds approximately to the minimal expected sharing between first cousins in an outbred population, resulting in a final GWAS sample size of 15,237

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8e), as manifested by increased PWL in the Hargreaves test

Instead, it resets three key metabolic levers: Satiety and Appetite Suppression: GLP-1 activates receptors in the hypothalamus and vagal afferent neurons, creating genuine signals of fullness

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Emerging brands like Replenza, Keptropy, and FullWell are marketing GLP-1-supportive supplements via direct-to-consumer channels, with emphasis on glycemic control, lean mass preservation, and post-meal tolerance