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Discontinue use if irritation, redness, or allergic reaction occurs and consult a dermatologist

The key point: contraindications are peptide-specific, not universal

It binds to specific penicillin-binding proteins (PBPs), inhibiting the transpeptidation step of peptidoglycan cross-linking, a crucial process in bacterial cell wall integrity

Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate OBV and Choline

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doi: 10.1136/gut.40.5.597