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doi: 10.1080/15548627.2023.2238577 35 KumariyaSUbbaVJhaRKGayenJR

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The DHODH-mediated ferroptosis defense mechanism not only deepens the understanding of the association between pyrimidine metabolism and cellular redox homeostasis but also provides experimental basis for targeting mitochondrial antioxidant systems in disease treatment, and exhibits potential value in intervening GPX4 deficiency-related diseases

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