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Another head-to-head trial against Wegovy (semaglutide) drove home the point: Mounjaro users lost about 20.2% of their body weight versus 13.7% for Wegovy users over 72 weeks Source : The New England Journal of Medecine

If it senses excessively high levels of IGF-1, it can signal the hypothalamus to stop producing GHRH and the pituitary to stop responding to it

Brain Res 199(2):359384 Da Cunha C, Angelucci ME, Canteras NS, Wonnacott S, Takahashi RN (2002) The lesion of the rat substantia nigra pars compacta dopaminergic neurons as a model for Parkinsons disease memory disabilities

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It also helps slow visible signs of aging by protecting skin cells from free-radical damage