To date, some possible protective agents, including sodium thiosulfate, acetyl-L-carnitine, resveratrol, Korean red ginseng, and N-acetylcysteine, have been tested and mechanisms determined against CDDP-induced sensorineural hearing loss in-vitro and invivo
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Miecz D, Januszewicz E, Czeredys M, Hinton BT, Berezowski V, Cecchelli R, et al
Statistical analysis in (G)(J) was done using one-way ANOVA versus vehicle, with signicance dened at p 3 and detected in more than 75% of the individual samples were quan- tied
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Intranasal administration has also been investigated in some preclinical models