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## How to Choose: A Decision Framework **Choose Semaglutide if** you want the most established safety profile, cardiovascular protection matters to you (SELECT trial data), you prefer the most affordable compounded option, or you are new to GLP-1 therapy and want a well-studied starting point

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The heart defects classified as CCHD include coarctation of the aorta, double-outlet right ventricle, D-transposition of the great arteries, Ebstein anomaly, hypoplastic left heart syndrome, interrupted aortic arch, pulmonary atresia with intact septum, single ventricle, total anomalous pulmonary venous connection, tetralogy of Fallot, tricuspid atresia, and truncus arteriosus

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PLoS One 6:e27260

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