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Its pathogenesis is characterized by immune system abnormalities, wherein the immune response targets normal tissues and organs, leading to inflammation and tissue damage ( Prolonged use of chloroquine and hydroxychloroquine can result in irreversible damage to the retinal pigment epithelium and the photoreceptor complex
Authors conclude that in contrast to dexamethasone that suppresses T cells overall, MSSM-002 is Th2-specific, at least partially, through GATA-3 regulation
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Heme A1M'ed at the kidney in sickle cell disease
Its the same pathway activated during exercise or caloric restriction, which is why those activities improve insulin sensitivity and metabolism