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8 Thyroid Tumor Risk: GLP-1 agonists have been shown to cause dose- and duration-dependent thyroid C-cell tumors in rodents

Judicial Panel on Multidistrict Litigation, there were 3,848 gastroparesis and other stomach and GI related cases in the GLP-1 gastrointestinal injury MDL and 146 NAION cases in the GLP-1 eye injury vision loss MDL, as of July 1, 2026

Mitochondrial content and function in skeletal muscle are regulated by GLP-1

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Importantly, new clinical evidence has shown that diabetic patients taking GLP-1 agonists are less likely to develop DED because of the anti-inflammatory effects on the lacrimal glands (2)

References: Carr, M