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Common symptoms include poor coordination and difficulty walking

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[10] [11] Sleep quality and duration profoundly affect metabolic health

Although excitotoxicity results from exacerbated excitatory transmission, it is important not to forget the relevance of GABAergic transmission and how GABAergic system modulators may affect neuronal plasticity and/or protect against cognitive decline after brain insults

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This paradigm shift makes cardiovascular outcomes in diabetes not only a clinical priority but also a core measure of therapeutic value