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This discrepancy may be because systemic injection blocks NMDA receptor function in the brain regions other than the dentate gyrus while NR1 gene removal in DG-NR1KO mice is specific to the dentate gyrus

While some individuals report improvements in symptoms, research is still developing, and peptides should generally be viewed as part of a broader arthritis management strategy

Convenient, though systemic exposure is lower than injectable

10.3389/fnmol.2014.00069 Front

11 , e10234 (2019)