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J Biol Chem 249: 75937602

West China 32 (6), 863867

Methionine is then converted into S-adenosylmethionine, which donates methyl groups in reactions catalyzed by methyltransferases, including DNA methylation, producing S-adenosylhomocysteine that is converted back into homocysteine

This rash, which may occur in conjunction with a fever, typically presents 12 weeks following the introduction of SMX therapy and often dissipates over a similar time course, within 12 weeks of withdrawal of the sulfonamide antimicrobial [4]