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This framing also explains why GLP-1s may be most effective early in the disease continuum, or as part of preventive strategies aimed at preserving cerebral blood flow, metabolic health, and mitochondrial resilience before irreversible neurodegeneration takes hold [14,15]

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Relief becomes steadier, flare-ups become less frequent, and the sense of cosntantly battling one issue after another finally quiets

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Clinical Review 29

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