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Storage conditions that shorten unopened shelf life: heat (extended exposure above 25C), freezing and re-thawing (can crack the stopper seal), direct sunlight (degrades benzyl alcohol), and humid environments (can degrade label readability and obscure exp date)

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Some clinicians combine both approaches, using PRP to deliver growth factors while simultaneously administering peptides to enhance cellular responsiveness

The clinical evidence base consists of separate studies examining each agent independently, without controlled investigation of their combination