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In practice, starting with a low dose and titrating slowly can help minimize side effects

Argaev-Frenkel L, Rosenzweig T

Moreover, our results revealed similarities and differences in neural pathways, which possibly regulated different metabolic effects of GLP-1RA and SGLT-2i via sympathetic and parasympathetic systems in the CNS, such as feeding, blood glucose regulation and cardiovascular activities (arterial blood pressure and heart rate control)

Semaglutide, a Glucagon Like Peptide-1 Receptor Agonist With Cardiovascular Benefits for Management of Type 2 Diabetes

GLP-1R agonists (GLP-1RAs) have many functions, such as neuroprotection, inhibiting infection, and metabolic regulation, and show good application prospects in improving cognitive function

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