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2017;49:e384

doi: 10.3389/fped.2025.1648282 Received 17 June 2025 Accepted 22 October 2025 Published 18 November 2025 Volume 13 - 2025 Edited by Ronan Lordan, University of Pennsylvania, United States Reviewed by Alex Staffler, Central Teaching Hospital of Bolzano/Bozen, Italy Anne Chiaramello, George Washington University, United States Updates Copyright 2025 Tan, Tewani, Anand, Kong, Rajadurai and Chandran

Funding in the J.A.L

No published human randomized trial has tested the CJC-1295 (no DAC) + Ipamorelin combination at the daily 200-300 mcg doses common online

Previous studies suggest that the peroxidation of polyunsaturated fatty acids in phospholipids by lipoxygenases (ALOX) is particularly important for ferroptosis [65, 66]

The clinical correlation between MetS and OA is robust, yet not all individuals with MetS develop severe OA, and vice versa