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Sporozoites were isolated from infected salivary glands on days 18 - 26 after the infective blood meal

For injectable: no reliable timeline because no good trial data exists

The reactive chemical 4-HNE is known to bind and form adducts to macromolecules including DNA [80], and cell culture studies demonstrate that Nrf2 and glutathione are needed to protect cells from 4-HNE and lipid peroxidation toxicity [81]

Early animal and small human studies suggest it is generally well tolerated in the short term, but we do not yet have large, longterm trials

The lowest activity of these enzymes was measured in the lenses with the CN and NP in relation to the PS cataract (table 5)

As a control, the non-responsive NHS-C7-NHS linker was used to covalently cross-link Mn@mHSA and TI@mHSA, resulting in the control formulation Mn/TI@mHSA-N, which had a similar size to Mn/TI@mHSA (Supplementary Fig