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Early-phase clinical trial data, including results from a Phase 2 trial published in The New England Journal of Medicine in 2023, demonstrated substantial weight reductions in some participants exceeding 20% of body weight over 48 weeks alongside a broadly manageable short-term adverse effect profile

J Biol Chem 288:74677480 Sikiric P (1999) The pharmacological properties of the novel peptide BPC 157 (PL-10)

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In children with ASD, a reduction in butyrate-producing bacteria with an enrichment of propionate producers may imbalance SCFA ratios, potentially affecting synaptic plasticity and neurotransmitter homeostasis

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