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A single-dose, direct brain injection of GLP-1-MK-801 has a more lasting effect on reducing food intake compared to an injection of semaglutide alone
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Women of childbearing potential should discuss contraception, as these medications should be avoided during pregnancy and discontinued prior to planned conception
Overall, the researchers estimated that GLP-1 drugs prevented roughly seven cases of substance use disorder and 12 incidents of serious harm for every 1,000 users over three years
10.1371/journal.pntd.0007362 PLoS Neg