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Resveratrol Resveratrol possesses anti-proliferative and anti-inflammatory effects by suppressing IL-17A, TNF-, and COX-2, and activating SIRT1 signaling pathways

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The addition of NAC to pirfenidone did not significantly affect the safety and tolerability profile of pirfenidone, but it did not appear to confer further benefits in terms of forced vital capacity, although it must be acknowledged that the study was underpowered to demonstrate a meaningful difference