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GeroScience 47 , 44134427 (2025)

EMA Decision P/0336/2024 Paediatric Investigation Plan: Retatrutide

This condition can lead to various pathological changes, including neuroinflammation, apoptosis of neurons, impaired BBB, synaptic plasticity deficiency, and mitochondrial dysfunction

Key factors influencing cost include: Regulatory status: Licensed medicines that have undergone full MHRA or EMA approval typically command higher prices than older, off-patent alternatives, reflecting the investment in clinical development and post-marketing surveillance